Bupropion Orion
This medicine is prescribed by your doctor to treat your depression by affecting brain chemicals like noradrenaline and dopamine.
Form
säädellysti vapauttava tabletti
Strength
150 mg
Active Ingredient
Bupropion hydrochloride
Manufacturer
Orion Corporation
How to Use
Dosage
The usual recommended dose for adults is one 150 mg tablet once a day.
Method
Take your Bupropion Orion tablet in the morning. Do not take it more than once a day. Swallow the tablets whole; do not chew, crush, or divide them.
Important
Your doctor may increase your dose to 300 mg once a day if your depression does not improve after several weeks.
Possible Side Effects
COMMON
- •Difficulty sleeping
- •Headache
- •Dry mouth
- •Nausea, vomiting
- •Fever
- •Dizziness
- •Itching, sweating, and rash (sometimes due to allergy)
- •Tremor, shakiness
- •Weakness, tiredness
- •Chest pain
- •Anxiety or agitation
- •Abdominal pain or other stomach problems (constipation)
- •Taste changes
- •Loss of appetite (anorexia)
- •Increased blood pressure (sometimes severe)
- •Flushing
- •Ringing in the ears
- •Visual disturbances
RARE
- •Depression (feeling sad)
- •Feeling confused
- •Lack of concentration
- •Increased heart rate
- •Weight loss
- •Seizures
- •Palpitations, fainting
- •Twitches, muscle stiffness, uncontrollable movements, problems with walking or coordination
- •Restlessness, irritability, hostility, aggressiveness, strange dreams, numbness or tingling, memory problems
- •Yellowing of the skin or whites of the eyes (jaundice), which may be due to increased liver enzyme levels, hepatitis
- •Severe allergic reactions, rash with joint and muscle pain
- •Changes in blood sugar levels
- •Increased or decreased need to urinate
- •Urinary incontinence (involuntary urination, urine leakage)
- •Severe rash in the mouth or other parts of the body that can be life-threatening
- •Worsening of psoriasis (reddish thickened skin patches)
- •Unusual hair loss or thinning (alopecia)
- •Feeling of unreality or strangeness (depersonalization), seeing or hearing things that are not there (hallucinations), believing things that are not true (delusions), strong suspiciousness (paranoia)
- •Suicidal thoughts and actions
- •Detachment from reality and inability to think clearly or make sound judgments (psychosis), including hallucinations and/or delusions
- •Sudden and intense fear (panic attack)
- •Stuttering
- •Decreased red blood cells (anemia), white blood cells (leukopenia), and platelets (thrombocytopenia)
- •Decreased blood sodium level (hyponatremia)
- •Changes in mental status (e.g., restlessness, hallucinations, coma) and other effects, such as body temperature over 38 °C, increased heart rate, unstable blood pressure and exaggerated reflexes, muscle stiffness, lack of coordination and/or gastrointestinal symptoms (e.g., nausea, vomiting, diarrhea), when taken with other antidepressants.
Important Warnings
- Do not take this medicine if you are allergic to bupropion or any of its ingredients. If you get signs of an allergic reaction like rash, swelling, or trouble breathing, contact a doctor right away and stop taking the tablets.
- Do not take this medicine if you are already taking other medicines that contain bupropion.
- Do not take this medicine if you have epilepsy or have had seizures in the past. If you have a seizure while taking this medicine, stop taking it and tell your doctor.
- Do not take this medicine if you have or have had an eating disorder like bulimia or anorexia nervosa.
- Do not take this medicine if you have a brain tumor.
Show 7 more warnings
- Do not take this medicine if you usually drink a lot of alcohol and have recently stopped or plan to stop drinking.
- Do not take this medicine if you have severe liver problems.
- Do not take this medicine if you have recently stopped taking calming medicines or plan to stop them while on Bupropion Orion.
- Do not take this medicine if you are taking or have taken other depression medicines called MAOIs in the last 14 days.
- If you have thoughts of harming yourself or ending your life, contact a doctor immediately or go to the nearest hospital.
- This medicine may make you feel confused or dizzy. If this happens, do not drive or use tools or machines.
- This medicine is not recommended for people under 18 years old. Using antidepressants in those under 18 is linked to a higher risk of suicidal thoughts and actions.
Use in Elderly Patients
Category C
Suitable for older adults, with specific precautions. Consider risk of convulsions and numerous potential interactions. Reduce the dose already in mild renal impairment. Increases risk of falls. (updated 12.2.2024)