Buprenorphine G.L. Pharma
Buprenorphine G. L. Pharma is an opioid pain medication used to relieve severe pain after surgery in adults.
Form
resoribletti
Strength
0.2 mg
Active Ingredient
Buprenorphine hydrochloride
Manufacturer
G.L. Pharma GmbH
How to Use
Dosage
For adults, the usual dose is 0.2-0.4 mg every 6-8 hours as needed. For elderly patients, a single dose of 0.2 mg is often enough.
Method
Place the tablet under your tongue and let it dissolve for 5-10 minutes. If your mouth is dry, a few drops of liquid can help it dissolve faster. Do not suck, chew, or swallow the tablet. The tablet cannot be divided.
Important
Always follow your doctor's instructions for the maximum daily dose; generally, do not exceed 1.6 mg per day.
Possible Side Effects
COMMON
- •Feeling very sleepy
- •Dizziness
- •Spinning sensation (vertigo)
- •Nausea
- •Headache
- •Small pupils
- •Low blood pressure when standing up (dizziness when standing)
- •Shallow or slow breathing
- •Vomiting
- •Increased sweating
RARE
- •Confusion
- •Feeling of intense happiness (euphoria)
- •Nervousness
- •Depression
- •Psychotic disorder (trouble with reality)
- •Seeing or hearing things that aren't there (hallucinations)
- •Feeling detached from your body or self
- •Speech difficulties
- •Tingling or numbness
- •Coma
- •Shaking (tremor)
- •Blurred vision
- •Double vision
- •Vision impairment
- •Eye inflammation (conjunctivitis)
- •Ringing in the ears (tinnitus)
- •Fast heart rate (tachycardia)
- •Slow heart rate (bradycardia)
- •Bluish skin (cyanosis)
- •Type 2 heart block (a heart rhythm problem)
- •High blood pressure
- •Pale skin
- •Difficulty breathing
- •Temporary stop in breathing
- •Decreased appetite
- •Constipation
- •Indigestion
- •Gas (flatulence)
- •Itching
- •Skin rash
- •Difficulty emptying bladder
- •Weakness
- •Fatigue
- •General discomfort
- •Allergic reactions
- •Low mood
- •Restlessness (agitation with strong anxiety)
- •Seizures
- •Lack of coordination
- •Diarrhea
- •Hives (urticaria)
- •Tightening of airways (bronchospasm)
Important Warnings
- Do not take if you are allergic to buprenorphine, other opioid pain medicines, or any other ingredients in this medicine.
- Do not take if you have severe breathing problems, severe liver disease, or confusion/poisoning from alcohol.
- Talk to your doctor before taking if you have any breathing problems (like asthma), head injuries, high pressure in your brain, a history of drug abuse, emotional instability, liver/kidney/adrenal gland problems, depression treated with certain medicines (risk of serotonin syndrome), sudden stomach pain, underactive thyroid, enlarged prostate, spinal problems affecting breathing, or if you've recently taken other strong painkillers or are dependent on opioids.
- Never give this medicine to anyone else. It can cause serious harm or even death if taken by someone it's not prescribed for.
- Avoid alcohol and other medicines that make you sleepy or slow your breathing, as this can make side effects worse and be dangerous.
Show 4 more warnings
- Do not use if you are pregnant or breastfeeding without consulting your doctor, as buprenorphine passes into breast milk and can harm the baby.
- This medicine can make you drowsy or dizzy. Do not drive or operate machinery if you feel drowsy or dizzy.
- This medicine can cause sleep-related breathing problems (like sleep apnea). If you or others notice symptoms like pauses in breathing during sleep or excessive daytime sleepiness, contact your doctor.
- Stop taking this medicine and seek immediate medical help if you experience signs of a severe allergic reaction (like swelling of the face/throat, difficulty breathing, fast heartbeat, dizziness, sweating, or loss of consciousness) or severe swelling of the face, neck, or throat (angioedema), which can be life-threatening.
Use in Elderly Patients
Category C
Suitable for older adults, with specific precautions. Sedative. Low transdermal efficacy in cachectic patients. Increases the risk of confusion and falling. Need for laxative is often necessary. (updated 24.3.2025)