Bugvi
Bugvi is a cancer medicine that stops cancer cells from growing and dividing.
Form
infuusiokuiva-aine, dispersiota varten
Strength
5 mg/ml
Active Ingredient
Paclitaxel
Manufacturer
STADA Arzneimittel AG
How to Use
Dosage
The typical dose for breast cancer is 260 mg per square meter of body surface area (mg/m²).
Method
A doctor or nurse will give you this medicine as an intravenous infusion (drip into a vein) over 30 minutes.
Important
Your doctor will determine your appropriate dose and treatment schedule, as this medicine is not typically taken daily.
Possible Side Effects
COMMON
- •Hair loss
- •Skin rash
- •Low white blood cell count, increasing infection risk
- •Low red blood cell count (anemia), causing tiredness and weakness
- •Low platelet count, increasing bleeding risk
- •Nerve problems in hands and feet (pain, numbness, tingling, or loss of feeling)
- •Pain in joints and muscles
- •Nausea, vomiting, diarrhea, constipation, sore mouth, loss of appetite
- •Weakness, tiredness, fever
- •Dehydration, changes in taste, weight loss
- •Low potassium levels in blood
- •Depression, sleep problems
- •Headache
- •Chills
- •Dizziness
- •Difficulty breathing
- •Swelling in mucous membranes and soft tissues
- •Elevated liver test results
- •Pain in arms and legs
- •Cough
- •Stomach pain
- •Nosebleeds
- •Itching, dry skin, changes in nails
- •Infections with fever and reduced white blood cells, redness, thrush, severe blood infection
- •Reduced counts of all blood cells
- •Chest or throat discomfort
- •Indigestion, stomach upset
- •Blocked nose
- •Back and bone pain
- •Poor muscle coordination, difficulty reading, changes in tear production, eyelash loss
- •Changes in heart rhythm or rate, heart failure
- •Low or high blood pressure
- •Redness or swelling at the injection site
- •Anxiety
- •Lung infection (pneumonia)
- •Urinary tract infection
- •Bowel obstruction, inflammation of the colon or bile ducts
- •Acute kidney failure
- •High bilirubin levels in blood
- •Coughing up blood
- •Dry mouth, difficulty swallowing
- •Muscle weakness
- •Blurred vision
RARE
- •Weight gain, changes in blood test values (e.g., LDH, blood sugar, phosphorus), reduced kidney function
- •Weak or absent reflexes, involuntary movements, nerve pain, fainting, dizziness when standing, tremor, facial nerve paralysis
- •Eye irritation, pain or redness in eyes, itchy eyes, double vision, reduced vision or flashing lights, blurred vision due to retinal swelling
- •Ear pain, ringing in ears
- •Cough with mucus, shortness of breath when walking or climbing stairs, runny or dry nose, reduced breathing sounds, fluid in lungs, loss of voice, blood clot in lungs, dry throat
- •Gas, stomach cramps, sore or tender gums, rectal bleeding
- •Painful or frequent urination, blood in urine, inability to hold urine
- •Nail pain, nail problems or loss, hives, skin pain, red skin from sun exposure, skin discoloration, increased sweating, night sweats, white skin patches, sores, facial swelling
- •Low blood phosphorus, fluid retention, low blood albumin, increased thirst, low blood calcium, low blood sugar, low blood sodium
- •Nasal pain and swelling, skin infections, catheter-related infection
- •Bruising
- •Pain at tumor site, death caused by tumor
- •Low blood pressure when standing, cold hands and feet
- •Walking difficulties, swelling
- •Allergic reaction
- •Impaired liver function, enlarged liver
- •Chest pain
- •Restlessness
- •Small skin bleeding caused by blood clots
- •A condition involving red blood cell destruction and acute kidney failure (Hemolytic Uremic Syndrome)
- •Skin reaction to another substance or lung inflammation after radiation therapy
- •Blood clot
- •Very slow pulse, heart attack
- •Leakage of medicine outside the vein
- •Disorder of heart's electrical activity (atrioventricular block)
- •Severe inflammatory skin and mucous membrane symptoms (Stevens-Johnson syndrome, toxic epidermal necrolysis)
- •Skin hardening/thickening (scleroderma)
Important Warnings
- Do not use Bugvi if you are allergic to paclitaxel or any other ingredient in this medicine.
- Do not breastfeed if you are using this medicine.
- Do not use Bugvi if you have a very low white blood cell count (your doctor will inform you).
- Do not use Bugvi if you are pregnant, planning to become pregnant, or are a woman of childbearing potential not using effective contraception.
- Tell your doctor if you have kidney problems.
Show 6 more warnings
- Tell your doctor if you have severe liver problems.
- Tell your doctor if you have heart problems.
- Tell your doctor if you experience unusual bruising, bleeding, or signs of infection like a sore throat or fever.
- Tell your doctor if you experience numbness, tingling, sensitivity to touch, or muscle weakness.
- Tell your doctor if you experience breathing difficulties, such as shortness of breath or a dry cough.
- Bugvi may cause tiredness or dizziness. Do not drive or operate machinery if you experience these symptoms.