Bosentan Accord

Bosentan Accord helps widen blood vessels in the lungs to lower high blood pressure there.

Form
tabletti, kalvopäällysteinen
Strength
62.5 mg
Active Ingredient
Bosentan monohydrate
Manufacturer
Accord Healthcare B.V.

How to Use

Dosage

Start with 62.5 mg twice a day for 4 weeks (morning and evening). Your doctor will then usually increase it to 125 mg twice a day.

Method

Swallow the tablets with water in the morning and evening. You can take them with or without food.

Important

The most you should take in a day is usually 250 mg (125 mg twice a day).

Possible Side Effects

COMMON
  • Headache
  • Swelling in legs and ankles
  • Hot flashes or red skin
  • Allergic reactions (skin redness, itching, rash)
  • Acid reflux
  • Diarrhea
  • Fainting
  • Fast or irregular heartbeat
  • Low blood pressure
  • Stuffy nose
RARE
  • Low numbers of blood cells (platelets, white blood cells)
  • Liver problems (changes in liver tests, liver inflammation, yellow skin/eyes)
  • Severe allergic reaction (swelling of face, lips, tongue, throat)
  • Liver scarring or liver failure
  • Blurred vision

Important Warnings

  • Do not take this medicine if you are allergic to bosentan or any of its ingredients.
  • Do not take this medicine if you have liver disease.
  • Do not take this medicine if you are pregnant, planning to get pregnant, or can get pregnant and are not using effective birth control. This medicine can harm an unborn baby.
  • Tell your doctor if you are breastfeeding. You should stop breastfeeding if you need to take Bosentan Accord.
  • Do not take this medicine if you are already taking cyclosporine A (a medicine used after organ transplants or for skin conditions).
Show 2 more warnings
  • Hormonal birth control (like the pill, injections, or patches) may not work well with Bosentan Accord. You must use other reliable birth control methods as well.
  • This medicine can cause dizziness or blurry vision because of low blood pressure. If you feel dizzy or your vision is blurry, do not drive or use machines.