Bortezomib Glenmark
Bortezomib Glenmark contains bortezomib and is used to treat cancers like multiple myeloma (a bone marrow cancer) and mantle cell lymphoma (a type of lymph node cancer) by destroying cancer cells.
Form
injektioneste, liuos
Strength
2.5 mg/ml
Active Ingredient
Bortezomib
Manufacturer
Glenmark Arzneimittel GmbH
How to Use
Dosage
Your doctor will decide your dose based on your height and weight; the usual starting dose is 1.3 mg per square meter of body surface area twice a week.
Method
The medicine is given as an injection into a vein (as a quick shot) or under the skin (into the thigh or stomach). A healthcare professional will administer the medicine.
Important
The medicine is usually given twice a week and is not taken daily.
Possible Side Effects
COMMON
- •Nerve damage causing skin sensitivity, numbness, tingling, or pain in hands or feet.
- •Decrease in red and/or white blood cell counts.
- •Fever.
- •Nausea and vomiting, reduced appetite.
- •Constipation, possibly with swelling (can be severe).
- •Diarrhea (drink more water if this happens).
- •Fatigue (tiredness), feeling weak.
- •Muscle pain, bone pain.
RARE
- •Low blood pressure, or a sudden drop in blood pressure when standing up, which can cause fainting.
- •High blood pressure.
- •Reduced kidney function.
- •Headache.
- •Infections such as pneumonia, respiratory infections, bronchitis, fungal infections, cough with mucus, flu-like illness, and shingles.
- •Swelling of the body, including around the eyes and other body parts.
- •Heart problems such as heart failure, heart attack, chest pain, or changes in heart rate.
- •Blood clots in veins or lungs.
- •Bleeding, for example, bloody stools, bleeding from mucous membranes (like in the mouth or vagina), or bleeding in the brain or liver.
- •Paralysis, seizures, movement disorders, changes in sensation (touch, hearing, taste, smell), problems with focus, tremors, muscle twitching, confusion, or memory loss.
- •Lung problems where your body doesn't get enough oxygen, such as difficulty breathing, shortness of breath, wheezing, or shallow breathing.
- •Yellowing of the eyes and skin (jaundice).
- •Severe allergic reactions (anaphylactic shock) with symptoms like difficulty breathing, chest pain, dizziness, severe itching, hives, or swelling of the face, lips, tongue, or throat.
- •Partial or complete vision loss.
Important Warnings
- Do not use this medicine if you are allergic to bortezomib, boron, or any other ingredient in this medicine.
- Do not use this medicine if you have severe lung or heart problems.
- Do not use this medicine if you are pregnant or breastfeeding, unless your doctor says it's absolutely necessary. Both men and women must use effective birth control during and for 3 months after treatment.
- This medicine can make you feel tired, dizzy, faint, or cause blurred vision. Do not drive or use machines if you experience these effects.
- Tell your doctor if you have low red or white blood cell counts, or bleeding problems with low platelet counts.
Show 11 more warnings
- Tell your doctor if you have diarrhea, constipation, nausea, or vomiting.
- Tell your doctor if you have fainted or felt dizzy before.
- Tell your doctor if you have kidney problems or moderate to severe liver problems.
- Tell your doctor if you have had numbness, tingling, or pain in your hands or feet (nerve damage).
- Tell your doctor if you have had heart problems or blood pressure issues.
- Tell your doctor if you have shortness of breath or a cough.
- Tell your doctor if you have had seizures.
- Tell your doctor if you have shingles (including around the eyes or spread across the body).
- Tell your doctor if you have symptoms of tumor lysis syndrome, such as muscle cramps, muscle weakness, confusion, vision loss, vision problems, and shortness of breath.
- Tell your doctor if you have memory loss, difficulty thinking, problems walking, or vision loss. These could be signs of a serious brain infection.
- Tell your doctor if you think you have or have had a hepatitis B infection.