Bivalirudin Reig Jofre
Bivalirudin Reig Jofre is a medicine that prevents blood clots and is used to treat chest pain from heart disease or during procedures to open narrowed blood vessels.
How to Use
Dosage
Your doctor will decide your exact dose based on your weight and treatment. For heart conditions, an initial injection of 0.1 mg per kg, followed by a drip of 0.25 mg per kg per hour for up to 72 hours, is common. For blood vessel opening procedures (angioplasty), an injection of 0.75 mg per kg, followed by a drip of 1.75 mg per kg per hour for up to 4 hours, is common.
Method
This medicine is given by injection into a vein, followed by a continuous drip (infusion) into a vein. It is never given into a muscle. A heart specialist will give and monitor it.
The maximum rate of administration is 1.75 mg per kg of body weight per hour during some procedures, and the total treatment duration is decided by your doctor.
Possible Side Effects
- •Minor bleeding
- •Significant bleeding (can occur internally and may be serious)
- •Anemia (low red blood cell count)
- •Bruising
- •Nausea and/or vomiting
- •Bleeding or bruising at the injection site
- •Low platelet count
- •Bleeding from gums
- •Allergic reactions (e.g., itching, rash, swelling)
- •Blood clots (thrombosis)
- •Increased INR test result
- •Chest pain
- •Slow or fast heart rate
- •Shortness of breath
- •Reperfusion injury (impaired blood flow in heart arteries after re-opening)
Important Warnings
- Do not use if you are allergic to bivalirudin or other blood thinners (hirudins).
- Do not use if you have active bleeding from your stomach, intestines, bladder, or other organs.
- Do not use if you have severe kidney problems or need dialysis.
- Do not use if you have severe, uncontrolled high blood pressure or a heart infection.
- Tell your doctor if you have had problems with blood clotting, like a low platelet count.
Show 3 more warnings
- Tell your doctor if you are taking other blood thinners, as this medicine can increase the risk of bleeding.
- This medicine is not for children under 18 years old.
- If you are pregnant or breastfeeding, talk to your doctor.