Bensylpenicillin Noridem
Bensylpenicillin Noridem is an antibiotic that kills certain bacteria causing infections in adults, teens, children, newborns, and premature babies.
Form
injektio-/infuusiokuiva-aine liuosta varten
Strength
6 g
Active Ingredient
Benzylpenicillin sodium
Manufacturer
Noridem Enterprises Limited
How to Use
Dosage
Your doctor will decide your dose based on your age, weight, and the severity of your infection. Doses are typically split into multiple administrations per day.
Method
A doctor or nurse will usually give you this medicine as an injection into a muscle or a vein. If given into a vein, it can be a quick shot or a slow drip (infusion) over 30 to 60 minutes.
Important
The maximum daily dose for adults can be up to 24 grams. For children and newborns, the maximum daily dose can be up to 0.6 grams per kg of body weight, depending on age and severity of infection.
Possible Side Effects
COMMON
- •Changes in lab test results
RARE
- •Allergic reactions
- •Hives (itchy rash)
- •Severe allergic reactions affecting the whole body or causing breathing problems (like asthma), skin bleeding, and stomach or bowel issues
- •Severe skin reactions, such as a rash with fever and blisters (erythema multiforme)
- •Widespread peeling skin inflammation (exfoliative dermatitis)
- •Fever
- •Joint pain
- •Inflammation of the mouth lining
- •Tongue inflammation, black hairy tongue
- •Nausea, vomiting
- •Electrolyte problems due to fast infusion of high doses
- •Nervous system disorders, including seizures with high dose infusions
- •Diarrhea; if severe, this could be a sign of colon inflammation.
- •Kidney disease
- •Abnormal amounts of albumin (protein) or blood in urine
- •Presence of sediment (casts) in urine
- •Reduced urine output or inability to urinate, usually improving within 48 hours after treatment stops
- •Severe local reactions at the injection site when given into a muscle, especially in babies
- •Increased number of white blood cells called eosinophils
- •Decreased number of white blood cells (like neutrophils or granulocytes), hemolytic anemia (decreased red blood cells), or a combination of these
- •Blood clotting disorders
- •Maculopapular rash (flat, red skin areas)
- •Measles-like rash
- •Itching
- •Erythema (inflammatory skin redness)
- •Angioedema (swelling of skin, mucous membranes, and tissue under the skin, usually in the face, mouth, or tongue)
- •Prolonged bleeding time and average time for blood to clot in tests
- •Thrombocytopenia (reduced number of platelets in the blood)
- •Serum sickness (an allergic reaction to proteins in the blood) with symptoms like fever, swollen lymph nodes, local redness at injection site, and itching
- •Jarisch-Herxheimer reaction, characterized by sudden fever, chills, skin redness, headache, muscle and joint pain, and tiredness
- •Metabolic encephalopathy (brain disorder with seizures and loss of consciousness)
- •Liver inflammation
- •Reduced bile flow in the gallbladder
- •Pemphigoid (a blistering skin disease)
Important Warnings
- Do not take this medicine if you are allergic to benzylpenicillin or any other penicillin antibiotic.
- Tell your doctor immediately if you have ever had a severe allergic reaction to penicillin, like a rash, itching, fever, trouble breathing, or low blood pressure. This medicine can cause a life-threatening allergic shock.
- Inform your doctor if you have had a severe allergic reaction to other antibiotics like cephalosporins or carbapenems.
- Seek immediate medical help if you get widespread rash with blisters and skin peeling, especially around the mouth, nose, eyes, and genitals (Stevens-Johnson syndrome), or a more severe form with widespread skin peeling (toxic epidermal necrolysis).