Bendamustine Avansor
Bendamustine Avansor is a medicine used to treat certain types of cancer.
Form
kuiva-aine välikonsentraatiksi infuusionestettä varten, liuos
Strength
2.5 mg/ml
Active Ingredient
Bendamustine hydrochloride
Manufacturer
Avansor Pharma Oy
How to Use
Dosage
Your doctor will determine the exact dose of Bendamustine Avansor based on your body size and condition.
Method
This medicine is given as a fast infusion into a vein over 30 to 60 minutes.
Important
The maximum daily dose and total number of treatment cycles will be determined by your doctor.
Possible Side Effects
COMMON
- •Low blood cell counts (white blood cells, red blood cells, platelets), increasing risk of infections, anemia, or bleeding.
- •Infections.
- •Headache.
- •Nausea and vomiting.
- •Inflammation of mucous membranes (e.g., mouth sores).
- •Increased kidney waste products (creatinine, urea) in the blood.
- •Fever.
- •Fatigue.
- •Bleeding.
- •Changes in body chemistry due to rapid breakdown of cancer cells (tumor lysis syndrome).
- •Anemia (low red blood cells causing paleness, weakness, shortness of breath).
- •Allergic reactions such as skin rash (dermatitis) and itchy hives (urticaria).
- •Increased liver enzyme levels (ASAT/ALAT, AFOS) which may indicate liver inflammation or damage.
- •Increased bilirubin (a substance from the breakdown of red blood cells).
- •Low potassium levels in the blood.
- •Heart problems like palpitations, chest pain, or irregular heartbeats.
- •Low or high blood pressure.
- •Breathing problems.
- •Diarrhea.
- •Constipation.
- •Loss of appetite.
- •Hair loss.
- •Skin changes.
- •Missed menstrual periods.
- •Pain.
- •Insomnia.
- •Dizziness.
- •Chills.
- •Dehydration.
RARE
- •Problems with bone marrow (myelodysplastic syndrome), leading to poor blood cell production or acute leukemia.
- •Fluid around the heart, heart attack, or heart failure.
- •Blood poisoning (sepsis).
- •Severe allergic reactions (anaphylaxis) or symptoms similar to anaphylaxis.
- •Drowsiness.
- •Hoarseness or loss of voice.
- •Sudden circulatory collapse (heart-related, affecting oxygen and nutrient supply).
- •Skin redness, various rashes (dermatitis, maculopapular), hives, or heavy sweating.
- •Atypical pneumonia.
- •Breakdown of red blood cells.
- •Sudden drop in blood pressure with skin reactions (anaphylactic shock).
- •Taste and sensation disorders.
- •Damage to peripheral nerves (discomfort and pain in limbs).
- •Nervous system disorders, including a severe condition affecting nerve receptors (anticholinergic syndrome), coordination problems (ataxia), or brain inflammation (encephalitis).
- •Rapid heart rate (tachycardia).
- •Vein inflammation (phlebitis).
- •Lung scarring (pulmonary fibrosis).
- •Esophageal or gastrointestinal bleeding.
- •Infertility (inability to have children).
- •Multiple organ failure.
Important Warnings
- Do not use if you are allergic to bendamustine hydrochloride or any other ingredients.
- Do not use if you are breastfeeding. You must stop breastfeeding if treatment is necessary.
- Do not use if you have severe liver problems or yellowing of the skin/eyes due to liver or blood issues.
- Do not use if your bone marrow is severely suppressed or if your white blood cell or platelet counts are very low.
- Do not use if you have had major surgery within the last 30 days.
Show 8 more warnings
- Do not use if you have an infection, especially with low white blood cell counts, or if you have received a yellow fever vaccine.
- Tell your doctor if you have a history of heart disease, such as heart attacks or chest pain.
- Tell your doctor if you feel very sick or vomit. Your doctor can prescribe medicine to help.
- Tell your doctor immediately if you have side pain, blood in your urine, or less urine, as this could be a serious problem (tumor lysis syndrome).
- Tell your doctor if you develop any skin rash, redness, or blistering, especially if it spreads or affects your mouth/lips.
- Tell your doctor immediately if you have a severe allergic reaction, such as swelling or difficulty breathing.
- Seek immediate medical help if you experience memory loss, trouble thinking, difficulty walking, or vision loss, as these could be signs of a rare, serious brain infection (PML).
- Contact your doctor if you notice any suspicious skin changes, as there might be an increased risk of certain skin cancers.