Apomorphine Stada
Apomorphine Stada is a medicine for Parkinson's disease that helps reduce 'off' periods (when movement is difficult) and immobility.
Form
infuusioneste, liuos, esitäytetty ruisku
Strength
5 mg/ml
Active Ingredient
Apomorphine hydrochloride
Manufacturer
STADA Arzneimittel AG
How to Use
Dosage
The usual infusion dose is 1–4 mg of apomorphine hydrochloride per hour.
Method
This medicine is given as a continuous infusion under the skin using a pump, not as single injections.
Important
The total amount of apomorphine hydrochloride you receive each day should not be more than 100 mg.
Possible Side Effects
COMMON
- •Painful, tender, red, and itchy lumps under the skin at the injection site. Change injection site each time to avoid these.
- •Seeing, hearing, or feeling things that are not real (hallucinations).
- •Nausea or vomiting, especially when you first start treatment. Taking anti-sickness medicine (domperidone) at least 2 days before Apomorphine Stada can prevent this.
- •Feeling very tired or very sleepy.
- •Feeling confused or having hallucinations.
- •Yawning.
- •Feeling dizzy or faint when standing up.
RARE
- •Increased involuntary movements or shaking during 'on' periods (when movement is better).
- •Hemolytic anemia (when red blood cells break down too quickly). This is rare and may occur in patients also taking levodopa.
- •Suddenly falling asleep.
- •Skin rashes.
- •Difficulty breathing.
- •Sores at the injection site.
- •Decreased red blood cells, which can make your skin look pale and cause weakness or shortness of breath.
- •Decreased platelets, which increases the risk of bleeding and bruising.
- •Allergic reaction with symptoms like skin rash, difficulty breathing, or swelling of the face, lips, throat, or tongue.
- •Eosinophilia (an abnormally high number of white blood cells in your blood or tissues).
- •Swelling in your legs, feet, or fingers.
- •Impulse control disorders, such as a strong urge to gamble, overeat, shop excessively, or have an increased sex drive.
- •Fainting.
- •Aggression, anxiety, restlessness.
- •Headache.
Important Warnings
- Do not use if you are under 18 years old.
- Do not use if you have breathing problems or asthma.
- Do not use if you have dementia or Alzheimer's disease.
- Do not use if you have confusion, hallucinations, or similar mental problems.
- Do not use if you have liver problems.
Show 5 more warnings
- Do not use if you have severe involuntary movements (dyskinesia) or inability to move (dystonia) despite taking levodopa.
- Do not use if you are allergic to apomorphine or any other ingredient in this medicine.
- Do not use if you or a family member have a heart condition called 'long QT syndrome'.
- Do not use if you are taking ondansetron (a medicine for nausea and vomiting).
- Tell your doctor if you or your family notice you developing unusual urges or strong desires to behave in ways that could harm you or others, such as gambling, overeating, excessive spending, or an increased sex drive.