Apixaban Krka
Apixaban Krka is a medicine that helps prevent blood clots by stopping a substance in your blood called factor Xa from working.
How to Use
Dosage
Your doctor will tell you the exact dose. It's usually one 2.5 mg or 5 mg tablet taken twice a day, depending on your condition and other factors. For blood clot treatment, it might start with a higher dose (two 5 mg tablets twice daily) for the first 7 days.
Method
Swallow the tablet whole with water, with or without food. Try to take it at the same time each day. If you have trouble swallowing, you can crush the tablet and mix it with water, glucose solution, apple juice, or applesauce right before taking it.
The maximum daily dose is usually 20 mg (four 5 mg tablets or eight 2.5 mg tablets) during the initial treatment for blood clots.
Possible Side Effects
- •Bleeding, including: bruises and swelling, bleeding in the eyes, stomach or intestines, rectum, urine, nose, gums, mouth, vagina, or after surgery.
- •Anemia (low red blood cells), which can cause tiredness or paleness.
- •Nausea.
- •Low blood pressure, which can cause faintness or a fast heartbeat.
- •Changes in blood tests, such as increased GGT or ALAT liver enzymes.
- •Rash.
- •Itching.
- •Low platelet count in blood, which can affect blood clotting.
- •Bleeding in the brain or spinal cord, lungs, throat, mouth with coughing up blood, muscles, eyes, gums, rectum, vagina, stomach, intestines, or around organs. Bleeding after surgery (bruises, swelling, fluid leakage from wounds) or from injection sites. Blood in urine/stools (visible or only in tests). Bleeding from hemorrhoids. Low platelet count (affects blood clotting).
- •Abnormal liver function, increased liver enzymes, or high bilirubin (causing yellow skin or eyes).
- •Hair loss.
- •Allergic reactions (hypersensitivity) that can cause swelling of the face, lips, mouth, tongue, and/or throat, and difficulty breathing. Seek immediate medical attention if these occur.
- •Skin rash with blisters that look like small targets (dark spot in the middle, surrounded by a paler area with a dark ring) (erythema multiforme).
- •Inflammation of blood vessels (vasculitis), which can cause skin rash, raised flat red or round spots under the skin, or bruising.
- •Bleeding in the kidney, sometimes with blood in the urine, leading to kidney problems (anticoagulant-related nephropathy).
Important Warnings
- You are allergic to apixaban or any other ingredients in this medicine.
- You are bleeding heavily.
- You have a condition that increases your risk of severe bleeding, such as a stomach ulcer or recent brain bleed.
- You have a liver disease that increases your bleeding risk.
- You are taking other medicines to prevent blood clots (like warfarin or heparin), unless you are switching treatments or using heparin for a catheter procedure.
Show 10 more warnings
- You have bleeding problems, including conditions where your platelets don't work well.
- You have very high blood pressure that is not controlled with medicine.
- You are over 75 years old or weigh 60 kg (about 132 lbs) or less.
- You have severe kidney disease or are on dialysis.
- You have or have had liver problems.
- You have had a spinal catheter or injection (for anesthesia or pain relief). Your doctor will tell you to take Apixaban Krka at least 5 hours after the catheter is removed.
- You have an artificial heart valve.
- You have antiphospholipid syndrome (an immune system disorder that increases blood clot risk).
- If you need surgery or a procedure that might cause bleeding, your doctor may ask you to stop this medicine temporarily.
- Do not stop taking Apixaban Krka without talking to your doctor first, as this increases your risk of blood clots.