Amoxin
Amoxin is an antibiotic containing amoxicillin, used to treat bacterial infections in various parts of the body.
Form
tabletti, kalvopäällysteinen
Strength
750 mg
Active Ingredient
Amoxicillin trihydrate
Manufacturer
ratiopharm GmbH
How to Use
Dosage
For adults, elderly, and children weighing 40 kg or more, the usual dose is 250-500 mg three times a day, or 750 mg-1 g every 12 hours, depending on the type and severity of the infection. For children weighing less than 40 kg, the usual dose is 40-90 mg per kg of body weight per day, divided into two or three doses.
Method
Take doses evenly throughout the day, with at least 4 hours between each dose.
Important
The maximum recommended daily dose for adults and children weighing 40 kg or more is 6 grams. For children weighing less than 40 kg, the maximum daily dose is 100 mg per kg of body weight.
Possible Side Effects
COMMON
- •Rash
- •Nausea
- •Diarrhea
RARE
- •Vomiting
- •Severe allergic reactions with itching, skin rash, swelling of the face, lips, tongue, or body, and difficulty breathing. These can be serious and, in rare cases, fatal.
- •Small, flat, red spots under the skin or bruises, caused by allergic inflammation of blood vessel walls, possibly with joint pain and kidney problems.
- •Delayed allergic reaction that may appear 7-12 days later, with rashes, fever, joint pain, and swollen lymph nodes, especially in the armpits.
- •A skin reaction called erythema multiforme, with itchy reddish-purple spots, hives, sore areas in the mouth, eyes, and genitals, possibly with fever and extreme tiredness.
- •Other severe skin reactions like changes in skin color, lumps under the skin, blisters, pus-filled blisters, peeling skin, redness, pain, itching, or flaking, sometimes with fever, headache, and body aches.
- •Flu-like symptoms with rash, fever, swollen glands, and abnormal blood test results (DRESS syndrome).
- •Fever, chills, sore throat, or other signs of infection, or easy bruising which may indicate blood cell problems.
- •Jarisch-Herxheimer reaction during Lyme disease treatment, causing fever, chills, headache, muscle pain, and rash.
- •Inflammation of the large intestine (colitis) with diarrhea (sometimes bloody), abdominal pain, and fever.
- •Severe liver problems, including severe diarrhea with bleeding, skin blisters, redness or bruising, dark urine, pale stools, or yellow skin/eyes (jaundice).
- •Yeast infection (in the vagina, mouth, or skin folds).
- •Kidney problems.
- •Convulsions (epileptic seizures), especially in patients taking high doses or with kidney problems.
- •Dizziness.
- •Hyperactivity.
- •Crystals in the urine, causing cloudy urine, difficulty or pain when urinating. Drink plenty of fluids to reduce this risk.
- •Tooth discoloration, which usually goes away with brushing (reported in children).
- •Tongue discoloration (yellow, brown, or black, sometimes appearing hairy).
- •Anemia (tiredness, headache, shortness of breath, dizziness, paleness, yellowing of skin and eyes) due to excessive breakdown of red blood cells.
- •Low white blood cell count.
- •Low platelet count (cells involved in blood clotting).
- •Blood clotting may take longer than usual (e.g., nosebleeds, bruising).
- •Inflammation of the membranes around the brain and spinal cord (aseptic meningitis).
- •Chest pain linked to allergic reactions, possibly a sign of allergy-induced heart attack (Kounis syndrome).
- •Drug-induced enterocolitis syndrome (DIES), mainly in children, with repeated vomiting, abdominal pain, lethargy, diarrhea, and low blood pressure.
- •Acute kidney damage due to crystals in the urine.
- •Blistering rash that forms circles with a crust in the center or pearl-like chains (linear IgA disease).
Important Warnings
- Do not use if you are allergic to amoxicillin, penicillin, or any other ingredients of this medicine.
- Do not use if you have had an allergic reaction to any antibiotic before (e.g., rash, swollen face or throat).
- Tell your doctor if you have glandular fever (mononucleosis).
- Tell your doctor if you have kidney problems or are not urinating regularly.
- Tell your doctor if you have had a severe skin rash with eosinophilia and systemic symptoms (DRESS) when taking other medicines.
Show 3 more warnings
- Inform your doctor or pharmacist if you are taking other medications like allopurinol (for gout), warfarin (blood thinner), tetracyclines (other antibiotics), methotrexate (for cancer/psoriasis), or probenecid (for gout).
- If you are pregnant, breastfeeding, or planning a pregnancy, consult your doctor or pharmacist before use.
- Amoxin can cause side effects like allergic reactions, dizziness, and convulsions, which may affect your ability to drive or operate machinery. Do not drive or use machines if you feel unwell.
Use in Elderly Patients
Category A
Suitable for older adults. Increase the dosing interval in severe renal impairment. May potentiate the effect of methotrexate. (updated 6.11.2023)