Amlodipin/Valsartan Orion
Amlodipin/Valsartan Orion is a medicine containing two active substances, amlodipine and valsartan, used to treat high blood pressure in adults whose blood pressure is not controlled by amlodipine or valsartan alone.
Form
tabletti, kalvopäällysteinen
Strength
5 mg / 80 mg
Active Ingredient
Amlodipine besylate
Manufacturer
Orion Corporation
How to Use
Dosage
The recommended dose is one tablet once daily.
Method
Take the tablet with a glass of water, at the same time each day, with or without food. Do not take with grapefruit or grapefruit juice.
Important
Do not exceed the prescribed dose. Your doctor may adjust your dose based on your response.
Possible Side Effects
COMMON
- •Flu-like symptoms, stuffy nose, sore throat and difficulty swallowing
- •Headache
- •Swelling of arms, hands, legs, ankles or feet
- •Tiredness
- •Weakness (asthenia)
- •Redness and hot flashes in face and/or neck
RARE
- •Dizziness
- •Nausea
- •Stomach pain
- •Dry mouth
- •Drowsiness
- •Tingling in hands or feet
- •Numbness in hands or feet
- •Vertigo (spinning sensation)
- •Fast heart rate
- •Palpitations
- •Dizziness when standing up
- •Cough
- •Diarrhea
- •Constipation
- •Rash
- •Skin redness
- •Joint swelling
- •Back pain
- •Joint pain
- •Restlessness
- •Ringing in the ears (tinnitus)
- •Fainting
- •More frequent urination
- •Increased urge to urinate
- •Inability to get or keep an erection
- •Feeling of pressure or heaviness
- •Low blood pressure, which may cause dizziness and confusion
- •Heavy sweating
- •Rash all over the body
- •Itching
- •Muscle cramps
- •Decreased white blood cells
- •Decreased platelets, which may lead to unusual bruising or bleeding
- •High blood sugar (hyperglycemia)
- •Swollen gums
- •Swollen abdomen (gastritis)
- •Liver problems, liver inflammation (hepatitis), yellowing of the skin (jaundice), elevated liver enzymes
- •Increased muscle tension
- •Blood vessel inflammation, often with skin rash
- •Sensitivity to light
- •Disorders with stiffness, tremor, and/or movement problems
- •Intestinal swelling (angioedema) with symptoms such as abdominal pain, nausea, vomiting, and diarrhea
- •Decreased red blood cells
- •Fever, sore throat or mouth ulcers due to infection
- •Spontaneous bleeding or bruising
- •High blood potassium levels
- •Abnormal liver test results
- •Impaired kidney function (including severely impaired)
- •Swelling mainly of the face and throat
- •Taste disturbances
- •Confusion
- •Weight gain or loss
Important Warnings
- Do not take this medicine if you are allergic to amlodipine, valsartan, or any other ingredient in this medicine.
- Do not take this medicine if you have severe liver problems or bile duct problems, such as biliary cirrhosis or cholestasis.
- Do not use this medicine if you are pregnant after the third month, and avoid use in early pregnancy as it can harm your baby.
- Do not take this medicine if you have very low blood pressure (hypotension).
- Do not take this medicine if you have narrowing of the aortic valve (aortic stenosis), cardiogenic shock (when your heart cannot pump enough blood), or heart failure after a heart attack.
Show 5 more warnings
- Do not take this medicine if you have diabetes or kidney problems and are being treated with a blood pressure-lowering medicine containing aliskiren.
- If you experience sudden swelling, especially of the face, lips, tongue, or throat, or difficulty breathing, stop taking this medicine immediately and contact your doctor. Never take it again.
- Contact your doctor immediately if you develop severe skin reactions like widespread rash, hives, redness all over the body, severe itching, blistering, peeling skin, or inflamed mucous membranes.
- Contact your doctor immediately if you experience a heart attack or abnormal heart rate.
- Contact your doctor immediately if you have inflammation of the pancreas, causing severe stomach pain and back pain, and making you feel very unwell.
Use in Elderly Patients
Category A
Suitable for older adults. Monitor renal function and potassium concentrations during the pharmacotherapy. Avoid concurrent use of NSAIDs. (updated 14.4.2025)