Amlodipin Accord
Amlodipin Accord is a calcium channel blocker used to treat high blood pressure and chest pain (angina).
Form
tabletti
Strength
5 mg
Active Ingredient
Amlodipine besylate
Manufacturer
Accord Healthcare B.V.
How to Use
Dosage
The starting dose is 5 mg once daily, and can be increased to 10 mg daily; for children and adolescents (6-17 years), the usual starting dose is 2.5 mg daily, up to a maximum of 5 mg daily.
Method
Take the tablet once a day at the same time with a glass of water, with or without food. Do not take with grapefruit juice.
Important
For adults, a maximum of 10 mg daily. For children and adolescents (6-17 years), a maximum of 5 mg daily.
Possible Side Effects
COMMON
- •Edema (swelling due to fluid retention)
- •Headache
- •Dizziness
- •Drowsiness (especially at the beginning of treatment)
- •Palpitations
- •Flushing
- •Abdominal pain
- •Nausea
- •Changed bowel habits (diarrhea, constipation)
- •Indigestion
- •Fatigue
- •Weakness
- •Visual disturbances / double vision
- •Muscle cramps
- •Swollen ankles
RARE
- •Mood changes
- •Anxiety
- •Depression
- •Insomnia
- •Tremor
- •Taste changes
- •Fainting
- •Numbness or tingling in arms and legs
- •Loss of pain sensation
- •Ringing in ears
- •Low blood pressure
- •Sneezing/runny nose (rhinitis)
- •Cough
- •Dry mouth
- •Vomiting
- •Hair loss
- •Increased sweating
- •Itchy skin
- •Red patches on skin
- •Skin discoloration
- •Urination problems (increased need at night, increased frequency)
- •Erectile dysfunction / breast discomfort or enlargement in men
- •Pain / feeling unwell
- •Joint or muscle pain / back pain
- •Weight gain or loss
- •Confusion
- •Reduced white blood cells / reduced platelets (may cause easy bruising or bleeding)
- •High blood sugar (hyperglycemia)
- •Nerve disorder causing muscle weakness, tingling, or numbness
- •Swollen gums
- •Swollen abdomen (gastritis)
- •Liver problems (hepatitis, jaundice, high liver enzymes)
- •Increased muscle tension
- •Blood vessel inflammation with rash
- •Light sensitivity
- •Movement disorders (rigidity, tremor, slow movements, shuffling, unbalanced gait)
Important Warnings
- Do not take if you are allergic to amlodipine or other calcium channel blockers.
- Do not take if you have very low blood pressure.
- Do not take if you have certain severe heart conditions, such as aortic valve narrowing or cardiogenic shock.
- Do not take if you have heart failure after a heart attack.
- Do not eat grapefruit or drink grapefruit juice while taking this medicine.
Show 2 more warnings
- May affect your ability to drive or use machines. Do not drive if you feel sick, dizzy, or tired.
- Talk to your doctor if you have had a recent heart attack, heart failure, very high blood pressure, liver disease, or if you are elderly and your dose needs to be increased.
Use in Elderly Patients
Category A
Suitable for older adults. Significant adverse effects include ankle oedema and orthostatic hypotension. Consider potential interactions. Avoid grapefruit. (updated 17.2.2025)