Amitriptylin Abcur

Amitriptylin Abcur is a medicine used to treat depression, nerve pain, and to prevent chronic tension headaches and migraines in adults, as well as for bedwetting in children aged 6 and older.

Form
tabletti, kalvopäällysteinen
Strength
10 mg
Active Ingredient
Amitriptyline hydrochloride
Manufacturer
Abcur AB

How to Use

Dosage

Your doctor will tell you the right dose. For adults, it often starts at 10-25 mg, taken once or twice a day.

Method

Swallow the tablets whole with water, with or without food. Do not chew the tablets.

Important

The maximum daily dose for adults is usually 150 mg, but your doctor will decide what is best for you.

Possible Side Effects

COMMON
  • Drowsiness or sleepiness
  • Tremors (shaking of hands or other body parts)
  • Dizziness or lightheadedness
  • Headache
  • Fast, strong, or irregular heartbeat
  • Low blood pressure when standing up (causing dizziness)
  • Dry mouth
  • Constipation
  • Nausea (feeling sick)
  • Increased sweating
  • Weight gain
  • Slurred or slow speech
  • Aggression
  • Stuffy nose
  • Confusion
  • Changes in sex drive or ability (e.g., erectile problems)
  • Trouble focusing or paying attention
  • Changes in taste
  • Numbness or tingling in hands or feet
  • Coordination problems
  • Widened pupils
  • Heart block (problem with heart's electrical signals)
  • Tiredness
  • Low sodium levels in the blood
  • Agitation (physical restlessness)
  • Trouble urinating
  • Thirst
RARE
  • Agitation, anxiety, trouble sleeping, nightmares
  • Seizures
  • Ringing in the ears (tinnitus)
  • High blood pressure
  • Diarrhea or vomiting
  • Rash, hives, or swelling of the face and tongue
  • Increased breast milk production or leakage (without breastfeeding)
  • Increased pressure in the eye
  • Fainting
  • Worsening heart failure
  • Poor liver function (e.g., yellow skin or eyes, jaundice)
  • Decreased appetite or loss of appetite
  • Confusion or hallucinations (delirium, especially in older patients)
  • Abnormal heart rhythm or beats
  • Swollen salivary glands
  • Hair loss
  • Increased sensitivity to sunlight
  • Breast enlargement in men
  • Fever
  • Weight loss
  • Abnormal liver test results
  • Heart muscle disease
  • Feeling restless and needing to move constantly (akathisia)
  • Nerve damage (e.g., numbness or tingling in arms and legs)
  • Sudden eye pain and blurred vision (signs of acute glaucoma)
  • Severe constipation with stomach swelling, fever, and vomiting (due to paralyzed intestine)
  • Unusual bruising, bleeding, paleness, or long-lasting sore throat and fever (signs of blood problems)
  • Thoughts of self-harm or suicide

Important Warnings

  • Do not take this medicine if you are allergic to amitriptyline or any of its ingredients.
  • Do not take if you recently had a heart attack or have other serious heart problems like an irregular heartbeat.
  • Do not take if you are currently taking or have taken certain other medicines called MAOIs in the last 14 days, or moclobemide the day before.
  • Do not take if you have severe liver disease.
  • This medicine is not for children under 6 years old.
Show 4 more warnings
  • If you have depression, you might have thoughts of harming yourself or suicide. Talk to your doctor immediately if this happens.
  • Avoid alcohol while taking this medicine, as it can make you feel more drowsy.
  • This medicine can make you feel sleepy or dizzy, especially when you first start taking it. Do not drive or operate machines if you have these symptoms.
  • Tell your doctor if you have a slow heart rate, heart failure, other heart medicines, low potassium or magnesium, a very active thyroid, glaucoma, epilepsy, trouble urinating, an enlarged prostate, bipolar disorder, or schizophrenia.

Use in Elderly Patients

Category D

Avoid use in older adults. Anticholinergic. Sedative. Serotonergic. Risk of QT prolongation. Significant adverse effects include confusion, cognitive impairment, arrhythmias and orthostatic hypotension. Increases risk of falls. Consider the numerous potential interactions. Reduces the effectiveness of drugs for Alzheimer’s disease. (updated 12.2.2024)