Alprazolam Krka
Alprazolam Krka is a benzodiazepine medicine used to treat severe anxiety symptoms in adults for a short period.
Form
depottabletti
Strength
1 mg
Active Ingredient
Alprazolam
Manufacturer
KRKA d.d. Novo mesto
How to Use
Dosage
The usual starting dose is 0.5 mg once daily. The typical treatment dose is 0.5–3 mg per day, taken as a single dose or divided into two doses. For elderly or frail patients, the maximum daily dose should not exceed 0.5–1 mg.
Method
Swallow the prolonged-release tablet whole with water. Do not divide or crush it.
Important
The maximum daily dose is usually 3 mg, but for elderly or frail patients, it should not exceed 0.5–1 mg per day.
Possible Side Effects
COMMON
- •Feeling depressed
- •Feeling sedated, sleepy, or drowsy
- •Stumbling or having clumsy movements (ataxia)
- •Memory problems
- •Slurred speech
- •Dizziness
- •Headache
- •Constipation
- •Dry mouth
- •Tiredness
- •Irritability
- •Decreased or increased appetite
- •Confusion
- •Disorientation (not knowing where you are or what time it is)
- •Changes in sex drive (decreased or increased)
- •Anxiety
- •Insomnia (difficulty sleeping)
- •Nervousness
- •Balance problems
- •Coordination problems
- •Difficulty concentrating
- •Too much sleep
- •Tremors (shaking)
- •Blurred vision
- •Nausea
- •Vomiting
- •Skin inflammation (dermatitis)
- •Sexual dysfunction
- •Weight changes
RARE
- •Swelling of the face, tongue, or throat; difficulty swallowing; hives and breathing difficulties (Angioedema)
- •Yellowing of the skin and whites of the eyes (jaundice)
- •Agitation, restlessness, aggression, irritability, rage, delusions, nightmares, hallucinations, psychosis, or other behavioral disturbances (Paradoxical reactions)
- •Excessive high mood (mania or hypomania)
- •Hallucinations
- •Rage or agitation
- •Drug dependence or drug abuse
- •Memory loss
- •Feeling drunk-like
- •Muscle weakness
- •Incontinence
- •Irregular periods
- •Overproduction of the hormone prolactin
- •Aggressive or hostile behavior
- •Abnormal thoughts (delusions)
- •Hyperactivity
- •Nervous system imbalance (e.g., palpitations, increased salivation, nasal congestion)
- •Decreased alertness
- •Twisting or jerky movements (dystonia)
- •Digestive system disorders
- •Difficulty swallowing
- •Liver inflammation (hepatitis)
- •Abnormal liver function
- •Skin reaction due to sun sensitivity
- •Difficulty urinating
- •Swelling caused by fluid retention (peripheral edema)
- •Increased pressure in the eye
Important Warnings
- Do not take if you are allergic to alprazolam, other benzodiazepines, or any other ingredients in this medicine.
- Do not take if you have myasthenia gravis (a muscle weakening disease).
- Do not take if you have severe breathing problems, sleep apnea (breathing stops during sleep), or severe liver problems.
- Tell your doctor if the medicine's effect lessens after a few weeks or if you are worried about becoming dependent on it.
- Tell your doctor if you have a history of alcohol, drug, or substance abuse.
Show 10 more warnings
- Be aware that memory loss can occur, usually several hours after taking the medicine.
- Tell your doctor if you experience unusual reactions like restlessness, agitation, aggression, hallucinations, or behavioral changes, especially if you are elderly.
- Use with caution if you have chronic lung disease, kidney or liver problems, a mental illness, or if you are elderly, as this medicine can cause excessive sedation or muscle weakness, increasing the risk of falls.
- Avoid alcohol and talk to your doctor about other sedatives you are taking, as they can enhance the effect of Alprazolam Krka.
- This medicine has a risk of abuse, which can lead to overdose and death. Keep it out of reach of others.
- This medicine can increase the risk of hypomania or mania in patients with depression. It can also increase the risk of suicidal thoughts or actions. Contact your doctor immediately if you experience any of these symptoms or develop suicidal thoughts.
- Do not stop taking this medicine suddenly, as it can cause withdrawal symptoms like headache, muscle pain, severe anxiety, confusion, or seizures. The dose must be reduced gradually under medical supervision.
- Do not use during pregnancy unless strictly necessary and advised by your doctor, as it may harm the unborn baby. Do not breastfeed while using this medicine.
- Do not drive or operate machinery while taking this medicine, as it can cause drowsiness and affect your ability to concentrate.
- Using Alprazolam Krka with opioid medicines can be life-threatening, increasing the risk of drowsiness, breathing problems, and coma.
Use in Elderly Patients
Category D
Avoid use in older adults. Sedative. A long-acting. Increases the risk of drug addiction, cognitive disorder and traffic accidents. Increases risk of falls. Paradoxically, may increase anxiety, restlessness and aggression. (updated 15.1.2024)