Allopurinol Orion
Allopurinol Orion is a medicine used to prevent gout attacks and to treat other conditions where your body produces too much uric acid.
Form
tabletti
Strength
100 mg
Active Ingredient
Allopurinol
Manufacturer
Orion Corporation
How to Use
Dosage
Your doctor will usually start you on a low dose (e.g., 100 mg daily) to reduce side effects, then adjust it. Typical daily doses range from 100 to 900 mg, depending on your condition. For children under 15, the dose is typically 100-400 mg daily.
Method
Swallow the tablets whole or split with water after a meal. Drink plenty of fluids.
Important
The maximum daily dose can be up to 900 mg, but your doctor will decide your specific dose.
Possible Side Effects
COMMON
- •Skin rashes.
- •Increased levels of thyroid stimulating hormone in the blood.
RARE
- •Feeling sick (nausea), throwing up (vomiting), or diarrhea.
- •Allergic skin reactions, like an itchy rash.
- •Changes in liver tests.
- •Flu-like symptoms such as fever, chills, headache, and muscle pain.
- •General feeling of being unwell.
- •Severe skin changes, including sores in the mouth, throat, nose, or genitals, red/swollen eyes, widespread blistering, or skin peeling.
- •Severe allergic reactions with fever, rash, joint pain, and abnormal blood or liver tests, which can affect many organs.
- •Joint pain or painful swelling in areas like the groin, armpits, or neck.
- •Yellowing of the skin and eyes (jaundice).
- •Problems with liver or kidney function.
- •Kidney stones, with symptoms like blood in urine and pain in the stomach, side, or groin.
- •Blood in urine.
- •Changes in bowel habits or unusual smelly stools.
- •High fat levels in the blood.
- •Weakness, numbness, tingling, or unsteady walking.
- •Inability to move muscles (paralysis) or unconsciousness.
- •Convulsions, seizures, or depression.
- •Headache, dizziness, or drowsiness.
- •Vision problems, including cataracts (clouding of eye lenses).
- •Chest pain, high blood pressure, or a slow heart rate.
- •Swelling due to fluid retention (edema), especially in the ankles.
- •Male infertility, difficulty getting or keeping an erection, or ejaculation during sleep ('wet dreams').
- •Breast enlargement in men and women.
- •Changes in taste or mouth inflammation.
- •Boils (small, sore red bumps on the skin).
- •Hair loss or changes in hair color.
- •Thirst, fatigue, and weight loss (these could be symptoms of diabetes, and your doctor may check your blood sugar).
- •Swollen lymph nodes (this swelling usually goes away when you stop taking allopurinol).
- •Severe allergic reaction causing swelling of the face or throat.
- •Severe and potentially life-threatening allergic reaction.
- •Aseptic meningitis (inflammation of the membranes around the brain and spinal cord), with symptoms like a stiff neck, headache, nausea, fever, or confusion.
- •Lichenoid rash (an itchy, red/purple rash and/or white/grey lines on mucous membranes).
Important Warnings
- Do not take this medicine if you are allergic to allopurinol or any other ingredients.
- Do not take this medicine if you are currently having or have recently had a gout attack.
- Stop taking the medicine and contact your doctor immediately if you develop a skin rash or other serious skin reactions.
- Tell your doctor if you have liver or kidney problems, as your dose may need to be adjusted.
- Inform your doctor if you have heart problems, high blood pressure, or thyroid problems.
Show 3 more warnings
- This medicine can cause dizziness and drowsiness. Do not drive or operate machinery if you feel affected.
- The 300 mg tablets contain a dye (para-orange, E110) which is not recommended for children under 15 years and may cause allergic reactions. This medicine also contains lactose.
- Allopurinol is not recommended during breastfeeding. If you are pregnant or planning a pregnancy, talk to your doctor.
Use in Elderly Patients
Category C
Suitable for older adults, with specific precautions. Reduce the dose already in mild renal impairment. Consider potential interactions. (updated 16.9.2024)