Allopurinol Accord
Allopurinol Accord helps your body control the speed of certain chemical changes and is used when your body produces too much uric acid.
Form
tabletti
Strength
100 mg
Active Ingredient
Allopurinol
Manufacturer
Accord Healthcare B.V.
How to Use
Dosage
Your doctor will start you on a low dose, usually 100-300 mg per day, and may increase it as needed. For children under 15, the dose is 10-20 mg/kg per day.
Method
Take the tablets by mouth with a glass of water, preferably after a meal to reduce stomach upset.
Important
The maximum daily dose for adults is 900 mg. For children under 15, the maximum daily dose is 400 mg.
Possible Side Effects
COMMON
- •Rash
- •Increased levels of thyroid-stimulating hormone (TSH) in blood
- •Nausea, vomiting
- •Abnormal liver function tests
- •Diarrhea
RARE
- •Liver problems, such as hepatitis
- •High body temperature
- •Blood in urine (hematuria)
- •High cholesterol levels in blood (hyperlipidemia)
- •General feeling of being unwell or weak
- •Weakness, numbness, shaky legs, inability to move muscles (paralysis), or loss of consciousness; headache, dizziness, drowsiness, or vision problems
- •Chest pain (angina pectoris), high blood pressure, or slow heart rate
- •Fluid retention and swelling (edema), especially in the ankles
- •Glucose metabolism disorders (diabetes), your doctor may check your blood sugar levels
- •Changes in blood quality (easier bruising, sore throat, or signs of infection)
- •Effects on lymph nodes
- •Male infertility, impotence, or breast enlargement in both men and women
- •Changes in bowel habits
- •Taste changes
- •Cataracts
- •Hair loss or hair discoloration
- •Depression
- •Problems with muscle coordination (ataxia)
- •Tingling, prickling, or burning sensation on the skin (paresthesia)
Important Warnings
- Do not take this medicine if you are allergic to allopurinol or any other ingredients.
- Tell your doctor if you have or have had liver, kidney, heart problems, high blood pressure, or thyroid problems.
- Do not take Allopurinol Accord during an acute gout attack.
- Stop taking this medicine immediately and contact your doctor if you develop a skin rash, especially if you are of Han Chinese, Thai, or Korean origin, as this medicine can cause severe skin reactions.
- If you have kidney stones, this medicine might make them smaller, which could cause them to move and block your urinary tract.
Show 1 more warnings
- If you have cancer or Lesch-Nyhan syndrome, drink plenty of fluids to dilute your urine, as uric acid levels in your blood may increase.
Use in Elderly Patients
Category C
Suitable for older adults, with specific precautions. Reduce the dose already in mild renal impairment. Consider potential interactions. (updated 16.9.2024)