Troppi LogoTroppi
ENFISV

Alitretinoin Orifarm

Alitretinoin Orifarm is a medicine used to treat severe, long-lasting hand eczema in adults when other treatments, including steroids, have not worked.

Form
kapseli, pehmeä
Strength
30 mg
Active Ingredient
Alitretinoin
Manufacturer
Orifarm Generics A/S

How to Use

Dosage

Take 10 mg or 30 mg once daily.

Method

Take the capsule whole with a main meal, preferably at the same time each day. Do not chew.

Important

The maximum recommended daily dose is 30 mg.

Possible Side Effects

COMMON
  • •Headache.
  • •High levels of fats in your blood (like cholesterol or triglycerides).
COMMON
  • •More platelets, fewer red and white blood cells in blood tests.
  • •Lower thyroid hormone levels.
  • •Dizziness.
  • •Eye inflammation (conjunctivitis) and eyelid inflammation; dry, irritated eyes.
  • •Ringing in the ears (tinnitus).
  • •Flushing (red face or skin).
  • •High blood pressure.
  • •Nausea, vomiting, dry mouth.
  • •Temporary changes in liver function tests.
  • •Dry skin (especially on the face), dry and inflamed lips, red skin, itchy rash, inflamed skin, hair loss.
  • •Joint pain, muscle pain, fatigue.
  • •High levels of muscle breakdown products in the blood if you exercise intensely.
RARE
  • •Vision problems such as blurred vision, distorted vision, cloudy eye surface (corneal clouding, cataracts), or decreased night vision.
  • •Increased pressure in the brain (headache, nausea, vomiting, pain behind the eyes, vision problems).
RARE
  • •Raised and itchy rash (hives), swelling around the eyes, mouth, or lips (angioedema) causing breathing difficulties or fainting due to a severe allergic reaction (anaphylaxis).
RARE
  • •Severe stomach pain, which may include bloody diarrhea, nausea, and vomiting.
RARE
  • •Overgrowth of bones, including spinal disease (ankylosing spondylitis).
RARE
  • •Indigestion (dyspepsia).
RARE
  • •Itching, skin flaking, rashes, dry skin eczema.
RARE
  • •Nosebleeds.
RARE
  • •Inflammation of blood vessels.
RARE
  • •Nail disorders.
RARE
  • •Increased skin sensitivity to sunlight.
RARE
  • •Changes in hair texture.
RARE
  • •Swelling of hands, feet, and ankles.
RARE
  • •Depression or similar mood disorders (sadness, mood swings, anxiety, emotional difficulties).
RARE
  • •Worsening of existing depression.
RARE
  • •Aggression or violence.
RARE
  • •Suicidal thoughts or attempts to harm oneself.
RARE
  • •Unusual behavior or psychosis (losing touch with reality, like hearing voices or seeing things that aren't there).
RARE
  • •Diabetes (signs include excessive thirst, frequent urination, high blood sugar).
RARE
  • •Color blindness, impaired color vision, or not being able to tolerate contact lenses.
RARE
  • •Arthritis, bone diseases (like delayed growth, changes in bone density), or bones stopping growth.

Important Warnings

  • This medicine can cause severe harm to an unborn baby. Women must use effective birth control. Do not take if you are pregnant or think you might be.
  • Do not take if you are allergic to alitretinoin, other retinoids (like isotretinoin), peanuts, soy, or any other ingredient in this medicine.
  • Do not take if you are breastfeeding.
  • Do not take if you have liver disease.
  • Do not take if you have severe kidney disease.
Show 11 more warnings
  • Do not take if you have high levels of fats in your blood (like high cholesterol or triglycerides).
  • Do not take if you have an untreated thyroid disease.
  • Do not take if you have very high levels of vitamin A in your body.
  • Do not take if you are taking tetracycline (a type of antibiotic).
  • Do not become pregnant for one month after stopping treatment.
  • Never give this medicine to anyone else. Return any unused capsules to the pharmacy after your treatment ends.
  • Do not donate blood during treatment or for one month after treatment ends.
  • Limit sun exposure and avoid sunbeds. Your skin may become more sensitive to sunlight. Use sunscreen with at least SPF 15.
  • Your night vision might get worse during treatment. If this happens, do not drive or use machines at night or in tunnels.
  • If you wear contact lenses, you may need to wear glasses during treatment with Alitretinoin Orifarm.
  • Tell your doctor if you have ever had mental health problems, including depression or thoughts of harming yourself.

Additional Information

ATC Code: D11AH04
→ View Professional Information (PDF)→ View Patient Leaflet (PDF)