Agomelatine Viatris
Agomelatine Viatris is an antidepressant medicine used to treat depression in adults.
Form
tabletti, kalvopäällysteinen
Strength
25 mg
Active Ingredient
Agomelatine citric acid cocrystal
Manufacturer
Viatris Limited
How to Use
Dosage
One 25 mg tablet in the evening before bedtime. Your doctor might sometimes prescribe 50 mg (two tablets) to be taken at once.
Method
Take the tablet whole with a glass of water. You can take it with or without food.
Important
Maximum of 50 mg per day (two tablets).
Possible Side Effects
COMMON
- •Headache
- •Dizziness
- •Sleepiness
- •Trouble sleeping (insomnia)
- •Feeling sick (nausea)
- •Diarrhea
- •Constipation
- •Stomach pain
- •Back pain
- •Tiredness
- •Anxiety
- •Unusual dreams
- •Increased liver enzymes in blood tests
- •Vomiting
- •Weight gain
RARE
- •Migraine
- •Tingling or numbness in fingers and toes
- •Blurred vision
- •Restless legs syndrome (an urge to move your legs)
- •Ringing in the ears (tinnitus)
- •Excessive sweating
- •Skin rash, itching, or hives
- •Agitation, irritability, restlessness, or aggressive behavior
- •Nightmares
- •Mania or hypomania (periods of unusual high energy or mood)
- •Thoughts of harming yourself or suicide
- •Confusion
- •Weight loss
- •Muscle pain
- •Severe skin rashes (reddening)
- •Swelling of the face, lips, tongue, and/or throat (angioedema), which can cause breathing or swallowing difficulties
- •Liver inflammation (hepatitis)
- •Yellowing of the skin or whites of the eyes (jaundice)
- •Liver failure (in rare cases leading to liver transplant or death)
- •Seeing or hearing things that are not there (hallucinations)
- •Inability to sit still (feeling physically and mentally restless)
- •Inability to fully empty the bladder
Important Warnings
- Do not take if you are allergic to agomelatine or any other ingredient in this medicine.
- Do not take if you have severe liver problems.
- Do not take if you are also taking fluvoxamine (another antidepressant) or ciprofloxacin (an antibiotic).
- If you notice signs of liver problems like dark urine, pale stools, yellow skin or eyes, upper right belly pain, or unusual tiredness, see a doctor right away.
- This medicine is not for people aged 75 years or older.
Show 4 more warnings
- If you have thoughts of harming yourself or suicide, contact a doctor or go to a hospital immediately.
- Avoid alcohol while taking this medicine.
- Do not breastfeed if you are taking this medicine.
- This medicine may cause dizziness or sleepiness, which can affect your ability to drive or use machines. Be sure your reactions are normal before driving or using machines.
Use in Elderly Patients
Category B
Current evidence on or experience with use in older adults is inconclusive or the medicine is insufficiently effective in the older adults. (updated 18.3.2024)